Mafia II is a third-person action-adventure video-game following the fictional story of a man of Sicilian descent who joins an Italian crime family in the period around 1950, a time when Italian crime families were near the height of their power and influence. It’s a familiar theme, having been portrayed in books, games, movies and television for decades.
UNICO National, the largest Italian American service organisation in the USA who have never seen or played the game, nor apparently been in contact with anyone who has (because at the time of their complaint, it had not been released) are calling it “a pile of racist nonsense” and demanding that the game not be released until all Italians and Italian-Americans are removed from it.
It strikes me that this would result in a rather substandard story.